Justin Yu Art

This piece of cover art depicts an anthropomorphized virion wearing a suit with a head shaped like an icosahedron, representing the Kaposi's Sarcoma-associated Virus (KSHV), a major focus of the Karijolich Lab. Jutting out from the back of the virion are a number of different mechanical elements, which are used to signify the synthetic nature of viruses, as they rely on a host's cellular machinery in order to reproduce. One gear is being removed by a disembodied hand. This represents the Karijolich Lab's research into the many mechanisms of KSHV infection, including the relationship between ORF36 and ISGylation.